With increasing commercial opportunities for biotherapeutics across global markets, demands are as high as ever for technologies that can support production of complex glycoproteins. N-linked glycosylation is a common post-translational modification to many proteins that may influence biological activity, protein conformation, stability, solubility, secretion, pharmacokinetics, and antigenicity.1
Consequently, the ability to control and tailor N-glycosylation is critical for today’s antibody engineering. With iBio’s new Glycaneering Development Service, we can provide the power, speed and control needed to develop next-gen monoclonal antibodies, biobetters, and fast-follower products.
Glycaneering is supported by iBio’s multi-attribute analytical methods, which uses mass spectrometry to elucidate and quantify precise glycoforms on recombinant proteins.